Important Safety Information
PRISTIQ® (desvenlafaxine) is a prescription
medication approved for the treatment of major
depressive disorder in adults.
Depression can make you
like you have to wind yourself
up to get through the day.
P R IS T IQ . Proven to treat depression.
Depression is a serious medical condition that can
take so much out of you. You may experience
erest, lack of energy,
affecting the levels
, serotonin and
PRISIIU may be a key in helping to treat your
depression. So ask your doctor about PRISTIQ.
EXTENDED
-RELEASE
TABLETS
Suicidality and Antidepressant Drugs
Antidepressants increased the risk compared
to placebo of suicidal thinking and behavior
(suicidality) in children, teens, and young adults.
Depression and certain other psychiatric
disorders are themselves associated with
increases in the risk of suicide. Patients of all
ages who are started on antidepressant therapy
should be monitored appropriately and observed
closely for clinical worsening, suicidality,
or unusual changes in behavior. PRISTIQ is not
approved for use in children under 18._______
• People taking MAOIs should not take PRISTIQ.
• All patients taking antidepressants should be observed
closely for signs that their condition is getting worse or
that they are becoming suicidal. This is very important
when an antidepressant is started or when the dose
is changed. Patients should be watched for becoming
agitated, irritable, hostile, aggressive, impulsive, or
restless. These symptoms should be reported to the
patient’s healthcare professional right away.
• Tell your healthcare professional about all
prescription and over-the-counter medications
you are taking or plan to take, including:
- Medicines to treat migraines or mood disorders,
to avoid a potentially life-threatening condition
- Aspirin, NSAID pain relievers, or blood thinners
because they may increase the risk of bleeding
• PRISTIQ may cause or make some conditions worse,
so tell your healthcare professional about all your
medical conditions, including if you:
- Have high blood pressure. Your blood pressure
should be controlled before you start taking
PRISTIQ and monitored regularly
- Have heart problems, high cholesterol or triglyceride
levels, or a history of stroke
- Have glaucoma or increased eye pressure
- Have kidney or liver problems
- Have or had mania, bipolar disorder, seizures,
or convulsions
- Have low sodium levels in your blood
- Are nursing, pregnant, or plan to become pregnant
• Discontinuation symptoms may occur when stopping
PRISTIQ, especially when therapy is stopped suddenly.
Talk to your healthcare professional before you stop
taking or reduce the dose of PRISTIQ.
• Until you see how PRISTIQ affects you, be careful
driving a car or operating machinery. Avoid drinking
alcohol while taking PRISTIQ.
• Side effects when taking PRISTIQ 50 mg may include
nausea, dizziness, sweating, constipation, and
decreased appetite.
If you do not have prescription drug
insurance and need help paying for
PRISTIQ, Wyeth may be able to help.
Visit us at www.wyeth.com or call us at
1-800-568-9938 for more information.
May 2009
247814-01
Visit Pristiq.com or call 1-800-PRISTIQ
Please see Brief Summary of
Prescribing Information on next page.
You are encouraged to report negative side
effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch,
or call 1-800-FDA-1088.
W yeth*
© 2009, Wyeth Pharmaceuticals Inc., Philadelphia, PA 19101
